Find 49 Deep Tech Angel Investors in the USA

We found 49 verified angel investors and VCs actively investing in Deep Tech startups in the USA.

Co-founder of 8VC. Expert in frontier tech, data analytics, and life sciences.

San Francisco, CASeries ASeries B
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Co-founder of Almaz Capital. Pioneer in post-Soviet tech investing. 30 year veteran.

Portola Valley, CASeries ASeries B
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Co-founder and CEO of Scale AI. Angel investor in AI infrastructure and data tooling.

San Francisco, CASeedSeries A
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Former OpenAI, former Tesla AI. Angel investor and advisor in deep learning and AI.

San Francisco, CAPre-SeedSeed
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Founder of Bill Lee Ventures. Investor in Tesla, SpaceX, Hyperloop. Close ally of Elon Musk.

Los Angeles, CASeries ASeries B
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Managing Director at ARCH Venture Partners. Pioneer biotech investor. 100+ biotech companies.

Chicago, ILSeedSeries ASeries B
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Co-founder of Oculus VR (acquired by Facebook for $2B). Angel in AR/VR and gaming.

San Francisco, CASeedSeries A
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Partner at Breakthrough Energy Ventures (Bill Gates). Expert in climate and energy tech.

Boston, MASeries ASeries B
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Managing Partner at Space Capital. Expert in GPS, satellite, and space infrastructure investing.

New York, NYSeedSeries ASeries B
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Angel and Partner at Long Journey. Former Founders Fund. Backed SpaceX, Uber, Postmates early.

San Francisco, CAPre-SeedSeed
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Former YC Partner and Apple AI lead. Active angel in AI startups and deep tech.

San Francisco, CASeedSeries A
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Partner at Breakthrough Energy Ventures. Former DOE Assistant Secretary. Clean energy expert.

San Francisco, CASeries ASeries B
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Founder of Innovation Endeavors. Eric Schmidt's VC fund. Expert in AI, robotics, climate.

Palo Alto, CASeedSeries A
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General Partner at LDV Capital. Expert in visual technology, AI, and computer vision.

New York, NYSeedSeries A
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Partner at a16z. Expert in AI and machine learning startups. Former AI researcher.

Menlo Park, CASeedSeries A
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Co-founder of OpenAI. Angel investor in AI infrastructure and safety.

San Francisco, CAPre-SeedSeed
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Co-founder of OpenAI and SSI. Pioneer in deep learning. Angel in AI safety research.

San Francisco, CASeedSeries A
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Co-founder of Lux Capital. Expert in science-driven deep tech and frontier technology.

New York, NYSeedSeries ASeries B
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Managing Director at Greentown Labs and investor in climate hardware startups.

Houston, TXPre-SeedSeed
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General Partner at a16z. Expert in American dynamism — defense, national security, manufacturing.

Menlo Park, CASeedSeries ASeries B
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Founder/CEO @

San Francisco, CASeedSeries A
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General Partner at Builders VC. Expert in frontier tech and life sciences.

San Francisco, CASeedSeries A
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Co-founder of PayPal and Founders Fund. Deep tech and defense investor.

Austin, TXSeedSeries A
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Founder of Humba Ventures. Pre-seed specialist for technical founders.

San Francisco, CAPre-Seed
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Co-founder of Pear VC. Former Stanford professor. Expert in AI and deep tech.

Palo Alto, CAPre-SeedSeed
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Partner at DCVC Bio. Expert in computational biology and AI for drug discovery.

San Francisco, CASeedSeries A
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Managing Partner at SpaceFund. Expert in new space economy and orbital infrastructure.

Houston, TXSeedSeries A
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Partner at Founders Fund. Expert in hard tech, energy, and defense.

San Francisco, CASeedSeries ASeries B
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Co-founder of Moderna and Flagship Pioneering. Builds breakthrough biotech companies.

Cambridge, MASeedSeries ASeries B
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Partner at Pear VC. Former early Dropbox. Expert in hard problems and technical founders.

San Francisco, CAPre-SeedSeed
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Partner at Xfund. Former general partner at NEA. Expert in deep tech and bio.

Cambridge, MASeedSeries A
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Co-founder of Lux Capital. Expert in frontier science and deep tech investing.

New York, NYSeedSeries ASeries B
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Co-founder of PayPal and Palantir. Founder of Founders Fund. Early investor in Facebook, LinkedIn.

Miami, FLSeedSeries ASeries B
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Managing Partner at Shield Capital. Former Deputy Assistant Secretary of Defense.

Arlington, VASeedSeries A
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Co-founder of Renegade Partners. Former partner at Lux Capital. Deep tech specialist.

San Francisco, CASeedSeries A
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Partner at XYZ Venture Capital. Ex-Village Global. Expert in deep tech and hard problems.

San Francisco, CAPre-SeedSeed
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Partner at Lux Capital. PhD from UCLA. Expert in robotics, autonomy, and hard tech.

Menlo Park, CASeedSeries A
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Founder of Celesta Capital. Former Intel Capital managing director. Deep tech expert.

San Jose, CASeedSeries ASeries B
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Serial entrepreneur and educator. Creator of Customer Development methodology. Angel advisor.

Pescadero, CAPre-SeedSeed
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Co-founder of Kindred Ventures. Expert in consumer and frontier technology.

San Francisco, CAPre-SeedSeed
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Co-founder of Apple. Active supporter and small angel in hardware and education tech.

Los Gatos, CAPre-Seed
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Partner at Founders Fund. Co-founder of Anduril. Expert in defense technology.

San Francisco, CASeedSeries ASeries B
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General Partner at a16z Bio. Expert in biotech and computational biology.

Menlo Park, CASeedSeries ASeries B
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Inventor of the Pentium chip. Active angel investor in semiconductor and deep tech.

San Jose, CASeedSeries A
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Founder of Khosla Ventures and co-founder of Sun Microsystems. Invests in deep tech, AI, and climate.

Menlo Park, CASeedSeries ASeries B
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General Partner at Kleiner Perkins. Expert in deep tech, quantum, and semiconductors.

Menlo Park, CASeries ASeries B
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Partner at Translink Capital. Expert in US-Japan and US-Korea cross-border investing.

San Jose, CASeries ASeries B
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World's most prestigious startup accelerator. Backed Airbnb, Stripe, Dropbox, Coinbase, Reddit.

San Francisco, CAPre-SeedSeed
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Partner at Breakthrough Energy Ventures. Expert in industrial decarbonization.

San Francisco, CASeries ASeries B
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Frequently Asked Questions

How to find Deep Tech angel investors in the USA?

If you are raising a round for your Deep Tech startup in the USA, you can use the OpenAngels database to access 49 verified active investors. We provide direct emails and LinkedIn profiles to help you pitch directly.

Who are the top Deep Tech investors for early-stage startups right now?

Currently, our database tracks 49 highly active Deep Tech investors. The list includes prominent angels and micro-VCs actively deploying capital this year.

Where can I get verified contact details for Deep Tech VCs?

OpenAngels aggregates and verifies contact information, including direct emails, for 49 Deep Tech investors, saving founders hundreds of hours of manual research.

Top 93 Deep Tech Angel Investors in the USA (2026) | OpenAngels