Find 53 AI Series A Angel Investors in San Francisco

We found 53 verified angel investors and VCs actively investing in AI startups at the Series A stage in San Francisco.

Co-founder of Base10 Partners. Expert in automation and future of work. African-American led fund.

San Francisco, CASeedSeries A
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Co-founder of 8VC. Expert in frontier tech, data analytics, and life sciences.

San Francisco, CASeries ASeries B
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Co-founder and CEO of Scale AI. Angel investor in AI infrastructure and data tooling.

San Francisco, CASeedSeries A
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General Partner at GV. Expert in life sciences and healthcare.

San Francisco, CASeries ASeries B
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Co-founder of Tribe Capital. Former partner at Social Capital. Data + product expert.

San Francisco, CASeedSeries A
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Partner at Fort Ross Ventures. Expert in Russian-American tech bridge investing.

San Francisco, CASeries ASeries B
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Managing Director at Zetta Venture Partners. First book on AI-first companies. Expert in enterprise AI.

San Francisco, CASeedSeries A
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Co-founder of Elance and Gupshup. Angel in messaging and marketplace startups.

San Francisco, CASeedSeries A
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Founder of SignalFire. Uses data + AI to source and back startups earlier than others.

San Francisco, CASeedSeries A
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Partner at Foresite Capital. Expert in biotech and life sciences investing.

San Francisco, CASeries ASeries Bgrowth
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Founder of CapitalX. Expert in AI and consumer companies from China and US.

San Francisco, CASeedSeries A
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Former YC Partner and Apple AI lead. Active angel in AI startups and deep tech.

San Francisco, CASeedSeries A
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Founder/COO @

San Francisco, CASeedSeries A
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CEO and Managing Partner at GV (Google Ventures). Led investments in Uber, Slack, Nest.

San Francisco, CASeedSeries ASeries B
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President of Salesforce Industries. Angel investor in vertical SaaS and enterprise AI.

San Francisco, CASeedSeries A
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Managing Director at General Catalyst. Former VP of Products at LinkedIn.

San Francisco, CASeries ASeries B
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Co-founder of Facebook and Asana. Active angel and co-founder of Open Philanthropy.

San Francisco, CASeedSeries A
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Partner at Race Capital. Expert in US-China tech bridge and Asian-American founders.

San Francisco, CASeedSeries A
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Serial entrepreneur and investor. Co-founder of Color Genomics. Backed Airbnb, Coinbase, Stripe early.

San Francisco, CASeedSeries A
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Co-founder of Twitch. Angel investor in gaming and consumer platforms.

San Francisco, CASeedSeries A
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General Partner at Benchmark. Led investments in Amplitude, Confluent, Ironclad. B2B SaaS expert.

San Francisco, CASeries ASeries B
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Managing Director at General Catalyst. Author of 'Intended Consequences'. Health and AI expert.

San Francisco, CASeedSeries ASeries B
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Co-founder of OpenAI and SSI. Pioneer in deep learning. Angel in AI safety research.

San Francisco, CASeedSeries A
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Partner at Bloomberg Beta. Expert in AI and the future of work. Author of AI roundup.

San Francisco, CASeedSeries A
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Co-founder and former CEO of Twilio. Angel investor in developer tools and API startups.

San Francisco, CASeedSeries A
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General Partner at a16z Bio + Health. Expert in healthcare technology transformation.

San Francisco, CASeries ASeries B
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Founder of Stitch Fix. Angel investor in retail tech and consumer brands.

San Francisco, CASeedSeries A
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Co-founder of Instagram. Angel investor in consumer and social products.

San Francisco, CASeedSeries A
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Partner at Sequoia Capital focused on AI and healthcare. Previously investor at Bessemer.

San Francisco, CASeedSeries ASeries B
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General Partner at GV. MD/MBA. Expert in life sciences and digital health.

San Francisco, CASeedSeries ASeries B
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Founder/CEO @

San Francisco, CASeedSeries A
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General Partner at Builders VC. Expert in frontier tech and life sciences.

San Francisco, CASeedSeries A
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CEO and Co-founder of Salesforce. Investor in enterprise SaaS and cloud companies.

San Francisco, CASeries ASeries B
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Partner at Index Ventures. Expert in B2B SaaS. Led investments in Webflow, Notion.

San Francisco, CASeedSeries A
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Founder of Zetta Venture Partners. Expert in AI and machine learning investing.

San Francisco, CASeedSeries A
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Co-founder of PayPal and Affirm. Active angel investor in fintech and consumer.

San Francisco, CASeedSeries A
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Partner at DCVC Bio. Expert in computational biology and AI for drug discovery.

San Francisco, CASeedSeries A
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Partner at Index Ventures USA. Former Cisco. Enterprise and infrastructure expert.

San Francisco, CASeries ASeries B
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Co-founder and Managing Partner at Audacious Ventures. Expert in future of work and B2B SaaS.

San Francisco, CASeedSeries A
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Partner at Founders Fund. Expert in hard tech, energy, and defense.

San Francisco, CASeedSeries ASeries B
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Former CEO of GitHub. Co-founder of Xamarin. Active angel in AI and developer tools.

San Francisco, CASeedSeries A
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Partner at Index Ventures. B2B SaaS and developer tools focus. Former McKinsey.

San Francisco, CASeedSeries A
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Co-founder and CEO of Stripe. One of the most respected founders in Silicon Valley.

San Francisco, CASeedSeries A
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Partner at Base10 Partners. Expert in automation tech for the real economy.

San Francisco, CASeedSeries A
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Co-founder of True Ventures. Expert in developer tools and open source.

San Francisco, CASeedSeries A
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Co-founder of Renegade Partners. Former partner at Lux Capital. Deep tech specialist.

San Francisco, CASeedSeries A
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CEO of OpenAI. Former president of Y Combinator. Prolific angel investor in AI and tech.

San Francisco, CAPre-SeedSeedSeries A
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Partner at 100 Plus Capital. Expert in longevity, biotech, and healthcare technology.

San Francisco, CASeedSeries A
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General Partner at a16z. Former Senior Director at Twitter, Microsoft, Snap. Expert in consumer and AI.

San Francisco, CASeedSeries A
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General Partner at Theory Ventures. Former Redpoint. Data-driven VC. Author of influential SaaS blog.

San Francisco, CASeedSeries A
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Founding Partner at Theory Ventures. Wrote the SaaS metrics bible. Expert in data-driven investing.

San Francisco, CASeedSeries A
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Partner at Founders Fund. Co-founder of Anduril. Expert in defense technology.

San Francisco, CASeedSeries ASeries B
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General Partner at GV. Expert in enterprise software and AI.

San Francisco, CASeries ASeries B
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Frequently Asked Questions

How to find Series A AI angel investors in San Francisco?

If you are raising a Series A round for your AI startup in San Francisco, you can use the OpenAngels database to access 53 verified active investors. We provide direct emails and LinkedIn profiles to help you pitch directly.

Who are the top AI investors for early-stage startups right now?

Currently, our database tracks 53 highly active AI investors. The list includes prominent angels and micro-VCs actively deploying capital this year.

Where can I get verified contact details for AI VCs?

OpenAngels aggregates and verifies contact information, including direct emails, for 53 AI investors, saving founders hundreds of hours of manual research.

Top 53 AI Series A Angel Investors in San Francisco (2026) | OpenAngels